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	<title>ChattahBox News Blog &#187; Science</title>
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	<link>http://chattahbox.com</link>
	<description>When There&#039;s News, Get Ready For Lots Of Chattah!</description>
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		<title>New procedure repairs severed nerves in minutes, restoring limb use in days or weeks</title>
		<link>http://chattahbox.com/science/2012/02/04/new-procedure-repairs-severed-nerves-in-minutes-restoring-limb-use-in-days-or-weeks/</link>
		<comments>http://chattahbox.com/science/2012/02/04/new-procedure-repairs-severed-nerves-in-minutes-restoring-limb-use-in-days-or-weeks/#comments</comments>
		<pubDate>Sat, 04 Feb 2012 16:25:15 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47827</guid>
		<description><![CDATA[American scientists believe a new procedure to repair severed nerves could result in patients recovering in days or weeks, rather than months or years. The team used a cellular mechanism similar to that used by many invertebrates to repair damage to nerve axons. Their results are published today in the Journal of Neuroscience Research. &#8220;We [...]]]></description>
			<content:encoded><![CDATA[<p>American scientists believe a new procedure to repair severed nerves  could result in patients recovering in days or weeks, rather than months  or years. The team used a cellular mechanism similar to that used by  many invertebrates to repair damage to nerve axons. Their results are  published today in the <em>Journal of Neuroscience Research</em>.</p>
<p>&#8220;We  have developed a procedure which can repair severed nerves within  minutes so that the behavior they control can be partially restored  within days and often largely restored within two to four weeks,&#8221; said  Professor George Bittner from the University of Texas. &#8220;If further  developed in clinical trials this approach would be a great advance on  current procedures that usually imperfectly restore lost function within  months at best.&#8221;</p>
<p>The team studied the mechanisms all animal  cells use to repair damage to their membranes and focused on  invertebrates, which have a superior ability to regenerate nerve axons  compared to mammals. An axon is a long extension arising from a nerve  cell body that communicates with other nerve cells or with muscles.</p>
<p>This  research success arises from Bittner&#8217;s discovery that nerve axons of  invertebrates which have been severed from their cell body do not  degenerate within days, as happens with mammals, but can survive for  months, or even years.</p>
<p>The severed proximal nerve axon in  invertebrates can also reconnect with its surviving distal nerve axon to  produce much quicker and much better restoration of behaviour than  occurs in mammals.</p>
<p>&#8220;Severed invertebrate nerve axons can  reconnect proximal and distal ends of severed nerve axons within seven  days, allowing a rate of behavioural recovery that is far superior to  mammals,&#8221; said Bittner. &#8220;In mammals the severed distal axonal stump  degenerates within three days and it can take nerve growths from  proximal axonal stumps months or years to regenerate and restore use of  muscles or sensory areas, often with less accuracy and with much less  function being restored.&#8221;</p>
<p>The team described their success in  applying this process to rats in two research papers published today.  The team were able to repair severed sciatic nerves in the upper thigh,  with results showing the rats were able to use their limb within a week  and had much function restored within 2 to 4 weeks, in some cases to  almost full function.</p>
<p>&#8220;We used rats as an experimental model to  demonstrate how severed nerve axons can be repaired. Without our  procedure, the return of nearly full function rarely comes close to  happening,&#8221; said Bittner. &#8220;The sciatic nerve controls all muscle  movement of the leg of all mammals and this new approach to repairing  nerve axons could almost-certainly be just as successful in humans.&#8221;</p>
<p>To  explore the long term implications and medical uses of this procedure,  MD&#8217;s and other scientist- collaborators at Harvard Medical School and  Vanderbilt Medical School and Hospitals are conducting studies to obtain  approval to begin clinical trials.</p>
<p>&#8220;We believe this procedure could produce a transformational change in the way nerve injuries are repaired,&#8221; concluded Bittner.</p>
<p>Contact: Ben Norman<br />
<a href="mailto:Lifesciencenews@wiley.com" target="_blank">Lifesciencenews@wiley.com</a><br />
44-012-437-70375<br />
<a href="http://www.wiley.com/wiley-blackwell" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.wiley.com/wiley-blackwell?referer=');">Wiley-Blackwell</a></p>
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		<title>Does antimatter weigh more, less or the same as matter?</title>
		<link>http://chattahbox.com/science/2012/01/26/does-antimatter-weigh-more-less-or-the-same-as-matter/</link>
		<comments>http://chattahbox.com/science/2012/01/26/does-antimatter-weigh-more-less-or-the-same-as-matter/#comments</comments>
		<pubDate>Thu, 26 Jan 2012 22:14:10 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47802</guid>
		<description><![CDATA[Does antimatter behave differently in gravity than matter? Physicists at the University of California, Riverside have set out to determine the answer. Should they find it, it could explain why the universe seems to have no antimatter and why it is expanding at an ever increasing rate. In the lab, the researchers took the first [...]]]></description>
			<content:encoded><![CDATA[<p>Does antimatter behave differently in gravity than matter? Physicists  at the University of California, Riverside have set out to determine  the answer. Should they find it, it could explain why the universe seems  to have no antimatter and why it is expanding at an ever increasing  rate.</p>
<p>In the lab, the researchers took the first step towards  measuring the free fall of &#8220;positronium&#8221;  &#8211;  a bound state between a  positron and an electron. The positron is the antimatter version of the  electron. It has identical mass to the electron, but a positive charge.  If a positron and electron encounter each other, they annihilate to  produce two gamma rays.</p>
<p>Physicists <a href="http://positron.ucr.edu/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/positron.ucr.edu/?referer=');">David Cassidy</a> and <a href="http://www.physics.ucr.edu/people/faculty/mills.html" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.physics.ucr.edu/people/faculty/mills.html?referer=');">Allen Mills</a> first separated the positron from the electron in positronium so that  this unstable system would resist annihilation long enough for the  physicists to measure the effect of gravity on it.</p>
<p>&#8220;Using lasers  we excited positronium to what is called a Rydberg state, which renders  the atom very weakly bound, with the electron and positron being far  away from each other,&#8221; said Cassidy, an assistant project scientist in  the <a href="http://www.physics.ucr.edu/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.physics.ucr.edu/?referer=');">Department of Physics and Astronomy,</a> who works in Mills&#8217;s lab. &#8220;This stops them from destroying each other  for a while, which means you can do experiments with them.&#8221;</p>
<p>Rydberg  atoms are highly excited atoms. They are interesting to physicists  because many of the atoms&#8217; properties become exaggerated.</p>
<p>In the  case of positronium, Cassidy and Mills, a professor of physics and  astronomy, were interested in achieving a long lifetime for the atom in  their experiment. At the Rydberg level, positronium&#8217;s lifetime increases  by a factor of 10 to 100.</p>
<p>&#8220;But that&#8217;s not enough for what we&#8217;re  trying to do,&#8221; Cassidy said. &#8220;In the near future we will use a technique  that imparts a high angular momentum to Rydberg atoms,&#8221; Cassidy said.  &#8220;This makes it more difficult for the atoms to decay, and they might  live for up to 10 milliseconds  &#8211;  an increase by a factor of 10,000  &#8211;   and offer themselves up for closer study.&#8221;</p>
<p>Cassidy and Mills  already have made Rydberg positronium in large numbers in the lab. Next,  they will excite them further to achieve lifetimes of a few  milliseconds. They will then make a beam of these super-excited atoms to  study its deflection due to gravity.</p>
<p>&#8220;We will look at the  deflection of the beam as a function of flight time to see if gravity is  bending it,&#8221; Cassidy explained. &#8220;If we find that antimatter and matter  don&#8217;t behave in the same way, it would be very shocking to the physics  world. Currently there is an assumption that matter and antimatter are  exactly the same  &#8211;  other than a few properties like charge. This  assumption leads to the expectation that they should both have been  created in equal amounts in the Big Bang. But we do not see much  antimatter in the universe, so physicists are searching for differences  between matter and antimatter to explain this.&#8221;</p>
<p>Study results appear in the Jan. 27 issue of <a title="Research paper" href="http://prl.aps.org/abstract/PRL/v108/i4/e043401" target="_blank" onclick="pageTracker._trackPageview('/outgoing/prl.aps.org/abstract/PRL/v108/i4/e043401?referer=');"><em>Physical Review Letters</em></a>.</p>
<p>Cassidy and Mills expect to attempt the next step in their gravity experiments this summer.</p>
<div>###</div>
<p>They were joined in the research by <a href="http://facultydirectory.ucr.edu/cgi-bin/pub/public_individual.pl?faculty=455" target="_blank" onclick="pageTracker._trackPageview('/outgoing/facultydirectory.ucr.edu/cgi-bin/pub/public_individual.pl?faculty=455&amp;referer=');">Harry Tom</a>, a professor of physics and astronomy, and Tomu H. Hisakado, a graduate student in Mills&#8217;s lab.</p>
<p>The research is being supported by grants from the National Science Foundation and the U.S. Air Force Research Office.</p>
<p><em>The University of California, Riverside (<a href="http://www.ucr.edu/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.ucr.edu/?referer=');">www.ucr.edu</a>)  is a doctoral research university, a living laboratory for  groundbreaking exploration of issues critical to Inland Southern  California, the state and communities around the world. Reflecting  California&#8217;s diverse culture, UCR&#8217;s enrollment has exceeded 20,500  students. The campus will open a medical school in 2013 and has reached  the heart of the Coachella Valley by way of the UCR Palm Desert Center.  The campus has an annual statewide economic impact of more than $1  billion. A broadcast studio with fiber cable to the AT&amp;T Hollywood  hub is available for live or taped interviews. UCR also has ISDN for  radio interviews. To learn more, call (951) UCR-NEWS. </em></p>
<p>Contact: Iqbal Pittalwala<br />
<a href="mailto:iqbal@ucr.edu" target="_blank">iqbal@ucr.edu</a><br />
951-827-6050<br />
<a href="http://www.ucr.edu/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.ucr.edu/?referer=');">University of California &#8211; Riverside</a></p>
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		<title>Mysterious monkey re-discovered in Borneo</title>
		<link>http://chattahbox.com/science/2012/01/22/mysterious-monkey-re-discovered-in-borneo/</link>
		<comments>http://chattahbox.com/science/2012/01/22/mysterious-monkey-re-discovered-in-borneo/#comments</comments>
		<pubDate>Sun, 22 Jan 2012 18:00:36 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47797</guid>
		<description><![CDATA[Simon Fraser University PhD student Brent Loken was hoping to capture images of the elusive Bornean clouded leopard when he set up a camera trap in the rainforest. Instead, he made the re-discovery of a lifetime. Reviewing time-lapse photos taken at a mineral lick in the Wehea Forest of East Kalimantan last June, he and [...]]]></description>
			<content:encoded><![CDATA[<p>Simon Fraser University PhD student Brent Loken was hoping to capture  images of the elusive Bornean clouded leopard when he set up a camera  trap in the rainforest. Instead, he made the re-discovery of a lifetime.</p>
<p>Reviewing time-lapse photos taken at a mineral lick in the  Wehea Forest of East Kalimantan last June, he and his fellow researchers  were stunned to see an animal they didn&#8217;t recognize. The pictures  showed Miller&#8217;s grizzled langur, one of the rarest and least-known  primates on the island of Borneo, and also a species many suggested was  extinct or on the verge of extinction.</p>
<p>&#8220;It was a challenge to  confirm our finding as there are so few pictures of this monkey  available for study,&#8221; says Loken, who is in SFU&#8217;s resource and  environmental management program. &#8220;The only description of Miller&#8217;s  grizzled langur came from museum specimens. Our photographs from Wehea  are some of the only pictures that we have of this monkey.&#8221;</p>
<p>Loken&#8217;s work is featured in a paper being published online this week in the <em>American Journal of Primatology</em> (print version, March 2012).</p>
<p>A  former secondary-school principal and science teacher, Loken holds both  Trudeau and Vanier scholarships. He spends up to six months each year  in Borneo where he runs Ethical Expeditions, a non-profit organization  he co-founded to help the indigenous Wehea Dayak people fight back  against deforestation. The island has lost 65 per cent of its  rainforest, largely due to palm oil plantations and coal mines.</p>
<p>&#8220;Finding  Miller&#8217;s grizzled langur in a forest outside of its known geographic  range highlights how much we don&#8217;t know about even the basic ecology of  this monkey,&#8221; says Loken. &#8220;We need more scientists doing research in  Borneo to help us learn about understudied species such as Miller&#8217;s  grizzled langur and clouded leopards. The rapid degradation of Borneo&#8217;s  forests makes it difficult to learn about and adopt conservation  strategies in time to protect species.&#8221;</p>
<p>Loken&#8217;s camera traps were  part of a larger biodiversity study he organized in collaboration with  the local Wehea Dayak community to investigate the diversity and  abundance of animals that were living in this remote forest.</p>
<div>Contact: Dixon Tam<br />
<a href="mailto:dixont@sfu.ca" target="_blank">dixont@sfu.ca</a><br />
778-782-8742<br />
<a href="http://www.sfu.ca/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.sfu.ca/?referer=');">Simon Fraser University</a></div>
<div></div>
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		<title>Balancing scientific freedom and national security</title>
		<link>http://chattahbox.com/science/2012/01/19/balancing-scientific-freedom-and-national-security/</link>
		<comments>http://chattahbox.com/science/2012/01/19/balancing-scientific-freedom-and-national-security/#comments</comments>
		<pubDate>Thu, 19 Jan 2012 21:24:38 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47792</guid>
		<description><![CDATA[The U.S. government&#8217;s request that the journals Science and Nature withhold scientific information related to the genetically modified H5N1 virus because of biosecurity concerns does not violate the First Amendment, say two Georgetown University professors. They caution, however, that a fair, transparent process undertaken by research organizations is preferable to governmental constraints on disseminating scientific [...]]]></description>
			<content:encoded><![CDATA[<p>The U.S. government&#8217;s request that the journals <em>Science</em> and <em>Nature</em> withhold scientific information related to the genetically modified  H5N1 virus because of biosecurity concerns does not violate the First  Amendment, say two Georgetown University professors. They caution,  however, that a fair, transparent process undertaken by research  organizations is preferable to governmental constraints on disseminating  scientific information.</p>
<p>Writing in <em>Science</em>, John D.  Kraemer, JD, MPH, assistant professor of health systems administration  at Georgetown University School of Nursing &amp; Health Studies, and  Lawrence O. Gostin, the Linda D. and Timothy J. O&#8217;Neill Professor of  Global Health Law and faculty director of the O&#8217;Neill Institute for  National and Global Health Law at Georgetown University Law Center,  explore the balance of scientific freedom and national security in their  opinion piece published online today entitled, &#8220;The Limits of  Government Regulation of Science.&#8221;</p>
<p>In 2011, two research teams  genetically modified the H5N1 avian influenza virus. Their work, funded  by the National Institutes of Health (NIH), demonstrates the ability to  alter a virus in such a way that it could possibly spread rapidly among  humans  &#8211;  killing more than half who contract it (the research was  conducted in an animal model believed to represent human behavior of the  virus). The research prompted the National Science Advisory Board for  Biosecurity (NSABB), which advises the Department of Health and Human  Services (HHS), to recommend that <em>Science</em> and <em>Nature</em> redact key information prior to publication. Both NSABB and HHS  expressed concerns that published details about the papers&#8217; methodology  and results could become a blueprint for bioterrorism.</p>
<p>&#8220;The NSABB  process seems to have worked well in this instance,&#8221; says Kraemer. &#8220;It  raised legitimate security concerns while avoiding censorship of the  scientific press. But there remains a need to strengthen precautions  around this type of research before it occurs.&#8221;</p>
<p>To date, <em>Science</em> and <em>Nature</em> have not yet announced their intentions regarding the government&#8217;s request.</p>
<p>In  their commentary, Kraemer and Gostin write &#8220;HHS&#8217; request reveals a  troubled relationship between security and science.&#8221; However, the  authors point out, &#8220;Given the absence of legal force or undue  inducements or penalties, the government&#8217;s request to withhold  information does not violate the First Amendment.&#8221;</p>
<p>Kraemer and  Gostin say the First Amendment, &#8220;affords considerable protection to  political artistic and scientific expression, triggering &#8216;strict  scrutiny&#8217; by the Supreme Court.&#8221; They point out that had the government  compelled either the researchers or the journals to withhold  publication, that act would have violated the First Amendment.</p>
<p>In  their opinion piece, the authors explore various court cases that  challenge and support the government&#8217;s rights to go further with such an  issue. They say the federal government has the power to prevent  dissemination of sensitive life science research, but warn, &#8220; there are  good reasons to exercise that power sparingly.&#8221;</p>
<p>Looking beyond  the current dilemma, Kraemer and Gostin ask: &#8220;Can the review process for  high-risk biologic research be improved further?&#8221;</p>
<p>The origins of  the National Science Advisory Board for Biosecurity can be traced to  the National Research Council&#8217;s Fink Report issued in 2004. The Fink  Report endorsed, among other things, expanded self-governance by  researchers toward issues of biosecurity, as well as the formation of a  national advisory board to help guide both the government and research  community in addressing issues involving dual-use research.</p>
<p>However,  Kraemer and Gostin point out that vital recommendations in the Fink  Report have not yet been implemented, including the need to employ an  institutional review process for biological &#8220;experiments of concern&#8221;  patterned on the Institutional Biosafety Committees (IBC) required for  recombinant DNA research.</p>
<p>Kraemer and Gostin make the following recommendations to improve the review process:</p>
<p>HHS,  in partnership with institutions, will have to ensure that the IBC  model works effectively: (1) institutions must develop the requisite  expertise to review dual use research; (2) HHS must specify the  categories of research requiring institutional review &#8211; minimally  including the 7 types of high-risk experiments; and (3) HHS must set  clear and consistent standards for institutional review. If IBCs are  formally designated to conduct the institutional review function, HHS  will have to clarify whether NSABB will guide and oversee the process.</p>
<p>Kraemer and Gostin suggest that such a process can ensure a, &#8220;sound  balance between scientific freedom and national security. A fair,  transparent process undertaken by research institutions, with a balanced  approach to scientific benefits and public safety, together with HHS  guidance and oversight of high-risk research, is preferable to  government constraints on scientific information by force of law.&#8221;</p>
<div>###</div>
<p><strong>About Georgetown University Law Center </strong></p>
<p>Georgetown  University Law Center is one of the world&#8217;s premier law schools. It is  pre-eminent in several areas, including constitutional, international,  tax and clinical law, and the faculty is among the largest in the  nation. Drawing on its Jesuit heritage, it has a strong tradition of  public service and is dedicated to the principle that law is but a  means, justice is the end. With this principle in mind, Georgetown Law  has built an environment that cultivates an exchange of ideas and the  pursuit of academic excellence. It brings together an extraordinarily  varied group of teachers, scholars and practitioners, as well as an  outstanding student body representing more than 60 countries.</p>
<p><strong>About Georgetown University Medical Center </strong></p>
<p>Georgetown  University Medical Center is an internationally recognized academic  medical center with a three-part mission of research, teaching and  patient care (through MedStar Health). GUMC&#8217;s mission is carried out  with a strong emphasis on public service and a dedication to the  Catholic, Jesuit principle of cura personalis &#8212; or &#8220;care of the whole  person.&#8221; The Medical Center includes the School of Medicine and the  School of Nursing &amp; Health Studies, both nationally ranked;  Georgetown Lombardi Comprehensive Cancer Center, designated as a  comprehensive cancer center by the National Cancer Institute; and the  Biomedical Graduate Research Organization (BGRO), which accounts for the  majority of externally funded research at GUMC including a Clinical  Translation and Science Award from the National Institutes of Health. In  fiscal year 2010-11, GUMC accounted for 85 percent of the university&#8217;s  sponsored research funding.</p>
<p>Contact: Karen Mallet<br />
<a href="mailto:km463@georgetown.edu" target="_blank">km463@georgetown.edu</a><br />
<a href="http://gumc.georgetown.edu/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/gumc.georgetown.edu/?referer=');">Georgetown University Medical Center</a></p>
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		<title>Research reveals power of the subconscious in human fear</title>
		<link>http://chattahbox.com/science/2012/01/18/research-reveals-power-of-the-subconscious-in-human-fear/</link>
		<comments>http://chattahbox.com/science/2012/01/18/research-reveals-power-of-the-subconscious-in-human-fear/#comments</comments>
		<pubDate>Wed, 18 Jan 2012 22:14:04 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47786</guid>
		<description><![CDATA[The human subconscious has a bigger impact than previously thought on how we respond to danger, according to research led by the University of Exeter. Published today (I8 January), the study shows that our primitive response to fear can contradict our conscious assessment of danger. The findings have implications for how anxiety disorders, such as [...]]]></description>
			<content:encoded><![CDATA[<p>The human subconscious has a bigger impact than previously thought on  how we respond to danger, according to research led by the University  of Exeter. Published today (I8 January), the study shows that our  primitive response to fear can contradict our conscious assessment of  danger.</p>
<p>The findings have implications for how anxiety  disorders, such as phobias, are treated. The research also suggests we  share a primitive response to fear with other animals, despite being  able to consciously anticipate and assess danger.</p>
<p>Participants  recruited to the study sat in front of a screen, on which a coloured  shape sometimes appeared. Half the time, the image was accompanied by a  mild electric shock. For the rest of the time, the image appeared but no  shock was given.</p>
<p>During the trial they were asked to rate  whether or not they expected a shock to be given and their &#8216;skin  conductance&#8217; was monitored. This technique measures the variation in the  electrical activity of the sweat glands in the skin, which is an  indication of the state of arousal of the sympathetic nervous system. In  other words, it gives us a reading of a person&#8217;s emotional state.</p>
<p>Following  a series of trials involving shocks, participants were more likely to  predict they would not receive a shock when the image was next shown.  The complementary result was that they generally anticipated receiving a  shock if they had not had one for the last few images. This phenomenon  of expecting good luck after a run of bad luck and vice versa, is known  as the &#8216;gambler&#8217;s fallacy&#8217;.</p>
<p>The skin conductance responses  revealed the opposite pattern. Following a series of shocks accompanying  the image, their physical responses to the next image shown suggested  participants were more likely to expect another shock, but that they  were less likely to expect a shock after a run of no-shock trials. This  pattern of responding is consistent with &#8216;associative learning&#8217;:  associating a visual cue with a significant event, a phenomenon that is  well known in animals.</p>
<p>Previously it has been thought that, when  using this type of procedure, humans respond differently from animals  because we rely on conscious reasoning, rather than associative learning  to generate our expectations. This study suggests that, despite our  sophisticated mental capabilities, our responses are in fact driven by  these more primitive processes when in danger.</p>
<p>Lead author,  Professor Ian McLaren of the University of Exeter said: &#8220;This research  clearly shows that, in these circumstances, our reaction to a  fear-provoking stimulus depends on a primitive response caused by  associative learning. This is something we share with other animals.</p>
<p>&#8220;This  could have important practical implications. Now that we know that  associative processes are implicated in our response to fear-inducing  stimuli, we need to consider the implications for the ways in which we  treat anxiety and phobias.&#8221;</p>
<p>Contact: Sarah Hoyle<br />
<a href="mailto:s.hoyle@exeter.ac.uk" target="_blank">s.hoyle@exeter.ac.uk</a><br />
44-013-927-22062<br />
<a href="http://www.exeter.ac.uk/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.exeter.ac.uk/?referer=');">University of Exeter</a></p>
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		<title>Potential new therapy approach for hepatitis C identified</title>
		<link>http://chattahbox.com/science/2012/01/16/potential-new-therapy-approach-for-hepatitis-c-identified/</link>
		<comments>http://chattahbox.com/science/2012/01/16/potential-new-therapy-approach-for-hepatitis-c-identified/#comments</comments>
		<pubDate>Mon, 16 Jan 2012 17:07:55 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47779</guid>
		<description><![CDATA[Researchers at the University of British Columbia have found a new way to block infection from the hepatitis C virus (HCV) in the liver that could lead to new therapies for those affected by this and other infectious diseases. More than 170 million people worldwide suffer from hepatitis C, the disease caused by chronic HCV [...]]]></description>
			<content:encoded><![CDATA[<p>Researchers at the University of British Columbia have found a new  way to block infection from the hepatitis C virus (HCV) in the liver  that could lead to new therapies for those affected by this and other  infectious diseases.</p>
<p>More than 170 million people worldwide  suffer from hepatitis C, the disease caused by chronic HCV infection.  The disease affects the liver and is one of the leading causes of liver  cancer and liver transplant around the world. HCV is spread by  blood-to-blood contact and there is no vaccine to prevent it. Current  treatments for the disease are only moderately effective and can cause  serious side effects.</p>
<p>&#8220;As HCV infects a person, it needs fat  droplets in the liver to form new virus particles,&#8221; says François Jean,  Associate Professor in the Department of Microbiology and Immunology and  Scientific Director of the Facility for Infectious Disease and Epidemic  Research (FINDER) at UBC. &#8220;In the process, it causes fat to accumulate  in the liver and ultimately leads to chronic dysfunction of the organ.&#8221;</p>
<p>&#8220;HCV  is constantly mutating, which makes it difficult to develop antiviral  therapies that target the virus itself,&#8221; says Jean. &#8220;So we decided to  take a new approach.&#8221;</p>
<p>Jean and his team developed an inhibitor  that decreases the size of host fat droplets in liver cells and stops  HCV from &#8220;taking residence,&#8221; multiplying and infecting other cells.</p>
<p>&#8220;Our  approach would essentially block the lifecycle of the virus so that it  cannot spread and cause further damage to the liver,&#8221; says Jean. The  team&#8217;s method is detailed in the journal <em>PLoS Pathogens</em>.</p>
<p>According  to Jean, HCV is one of a number of viruses that require fat to  replicate in the human body. This new approach to curbing the  replication of HCV could translate into similar therapies for other  related re-emerging viruses that can cause serious and life threatening  infections in humans, such as dengue virus. Dengue is endemic in more  than 100 countries, with approximately 2.5 billion people at risk of  infection globally. In some countries, Dengue has become the leading  cause of child mortality.</p>
<div>###</div>
<p>The  research was supported by the Canadian Institutes of Health Research  (CIHR) through grants and scholarships and by the Michael Smith  Foundation for Health Research (MSFHR) through its Junior Trainee Award.  The study is available at <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002468" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.plospathogens.org/article/info_doi/10.1371/journal.ppat.1002468?referer=');">http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002468</a></p>
<p>Contact: Brian Lin<br />
<a href="mailto:brian.lin@ubc.ca" target="_blank">brian.lin@ubc.ca</a><br />
604-822-2234<br />
<a href="http://www.ubc.ca/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.ubc.ca/?referer=');">University of British Columbia</a></p>
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		<title>I recognize you! But how did I do it?</title>
		<link>http://chattahbox.com/science/2012/01/14/i-recognize-you-but-how-did-i-do-it/</link>
		<comments>http://chattahbox.com/science/2012/01/14/i-recognize-you-but-how-did-i-do-it/#comments</comments>
		<pubDate>Sat, 14 Jan 2012 13:29:20 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47776</guid>
		<description><![CDATA[Are you someone who easily recognises everyone you&#8217;ve ever met? Or maybe you struggle, even with familiar faces? It is already known that we are better at recognising faces from our own race but researchers have only recently questioned how we assimilate the information we use to recognise people. New research by the University of [...]]]></description>
			<content:encoded><![CDATA[<p>Are you someone who easily recognises everyone you&#8217;ve ever met? Or  maybe you struggle, even with familiar faces? It is already known that  we are better at recognising faces from our own race but researchers  have only recently questioned how we assimilate the information we use  to recognise people.</p>
<p>New research by the University of Nottingham  Malaysia Campus has shown that when it comes to recognising people the  Malaysian Chinese have adapted their facial recognition techniques to  cope with living in a multicultural environment.</p>
<p>The study &#8216;You  Look Familiar: How Malaysian Chinese Recognise Faces&#8217; was led by  Chrystalle B.Y. Tan, a PhD student at the University of Nottingham  Malaysia Campus. The results have been published online in the  prestigious scientific journal <em>PloS One</em>, This research is the first PhD student publication for Nottingham&#8217;s School of Psychology in Malaysia.</p>
<p>Chrystalle  Tan said: &#8220;Our research has shown that Malaysian Chinese adopt a unique  looking pattern which differed from both Westerners and Mainland  Chinese, possibly due to the multicultural nature of the country.&#8221;</p>
<p>The  ability to recognise different faces may have social and evolutionary  advantages. Human faces provide vital information about a person&#8217;s  identity and characteristics such as gender, age, health and  attractiveness. Although we all have the same basic features we have our  own distinguishing features and there is evidence that the brain has a  specialised mental module dedicated to face processing.</p>
<p><strong>Recognition techniques</p>
<p></strong></p>
<p>Previous  research by a group at Glasgow University in Scotland showed that  Asians from mainland China use more holistic recognition techniques to  recognise faces than Westerners.</p>
<ul>
<li>Chinese focus on the centre of the face in the nose area</li>
<li>Westerners focus on a triangular area between the eyes and mouth</li>
<li>British born Chinese use both techniques fixating predominantly around either the eyes and mouth, or the nose</li>
</ul>
<p>Chrystalle  said: &#8220;The traditional view is that people recognise faces by looking  in turn at each eye and then the mouth. This previous research showed us  that some Asian groups actually focus on the centre of the face, in the  nose area. While Westerners are learning what each separate part of the  face looks like &#8211; a strategy that could be useful in populations where  hair and eye colour vary dramatically, mainland Chinese use a more  global strategy, using information about how the features are arranged.  Meanwhile British born Chinese use a mixture of both techniques  suggesting an increased familiarity with other-race faces which enhances  their recognition abilities.&#8221;</p>
<p><strong>Eye tracking technology</p>
<p></strong></p>
<p>The  study by the School of Psychology at the University of Nottingham  Malaysia Campus set out to investigate whether exposure and familiarity  with other cultures affects our recognition accuracy and eye movement  strategies.</p>
<p>The team used specialised eye tracking technology to  investigate the visual strategies used to recognise photographs of  faces. They recruited 22 Malaysian Chinese student volunteers from  across Nottingham&#8217;s Malaysia campus. The results showed that Malaysian  Chinese used a unique mixed strategy by focusing on the eyes and nose  more than the mouth.</p>
<p>Chrystalle said: &#8220;We have shown that  Malaysian Chinese adopt a unique looking pattern which differed from  both Westerners and mainland Chinese. This combination of Eastern and  Western looking patterns proved advantageous for Malaysian Chinese to  accurately recognise Chinese and Caucasian faces.&#8221;</p>
<p>The study was  supervised by Dr Ian Stephen, an expert on face processing and Dr  Elizabeth Sheppard, an expert in eye tracking. Dr Stephen said: &#8220;We  think that people learn how to recognise faces from the faces that they  encounter. Although Malaysia is an East Asian country its ethnic  composition is highly diverse. The intermediate looking strategy that  Malaysian Chinese use allows them to recognise Western faces just as  well as Asians.&#8221;</p>
<p>Contact: Lindsay Brooke<br />
<a href="mailto:lindsay.brooke@nottingham.ac.uk" target="_blank">lindsay.brooke@nottingham.ac.uk</a><br />
44-115-951-5751<br />
<a href="http://www.nottingham.ac.uk/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.nottingham.ac.uk/?referer=');">University of Nottingham</a></p>
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		<title>Planets around stars are the rule rather than the exception</title>
		<link>http://chattahbox.com/science/2012/01/12/planets-around-stars-are-the-rule-rather-than-the-exception/</link>
		<comments>http://chattahbox.com/science/2012/01/12/planets-around-stars-are-the-rule-rather-than-the-exception/#comments</comments>
		<pubDate>Thu, 12 Jan 2012 23:35:44 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47771</guid>
		<description><![CDATA[There are more exoplanets further away from their parent stars than originally thought, according to new astrophysics research. In a new paper appearing in the Jan. 12 edition of the journal, Nature, astrophysicist Kem Cook as part of an international collaboration, analyzed microlensing data that bridges the gap between a recent finding of planets further [...]]]></description>
			<content:encoded><![CDATA[<p>There are more exoplanets further away from their parent stars than originally thought, according to new astrophysics research.</p>
<p>In a new paper appearing in the Jan. 12 edition of the journal, <em>Nature</em>,  astrophysicist Kem Cook as part of an international collaboration,  analyzed microlensing data that bridges the gap between a recent finding  of planets further away from their parent stars and observations of  planets extremely close to their parent star. The results point to more  planetary systems resembling our solar system rather than being  significantly different.</p>
<p>Gravitational microlensing occurs when  light from a source star is bent and focused by gravity as a second  object (the lens star), which passes between the source star and an  observer on Earth. A planet rotating around the lens star will produce  an additional deviation in the microlensing. The first gravitational  microlensing observations were made by the Massive Astrophysical Compact  Halo Object (MACHO) collaboration, led by Livermore scientists.</p>
<p>The  new research also determines that a large fraction of planets have  orbital distances from 0.5 to 10 sun-Earth distances. In the past, using  the Doppler shift technique, most extrasolar planets found were gas  giants like Jupiter and Saturn that orbited stars that were much closer  to them than the sun is to Earth.</p>
<p>An exoplanet is a planet  outside our solar system. Over the past 16 years, astronomers have  detected more than 700 confirmed exoplanets and have started to probe  the spectra and atmospheres of these worlds. While studying the  properties of individual exoplanets is undeniably valuable, a much more  basic question remains: how commonplace are planets in the Milky Way?</p>
<p>The  team found that approximately 17 percent of stars host Jupiter-mass  planets. However, cool-Neptunes and super-Earths are more common,  occurring 52 percent and 62 percent, respectively, of the time.</p>
<p>Gravitationally microlensing is very rare. In fact, fewer stars than one per million undergo micolensing at any time.</p>
<p>The  team&#8217;s result is consistent with every star of the Milky Way, hosting,  on average, one planet or more in an orbital distance range of 0.5 to 10  sun-Earth distances.</p>
<p>&#8220;Our measurements confirm that low-mass  planets are very common and the number of planets increases with  decreasing planet mass, in an agreement with the predictions of the core  accretion scenario of planet formation,&#8221; Cook said. &#8220;Planets around  stars in our galaxy appear to be the rule rather than the exception.&#8221;</p>
<p>&#8220;We  used to think that the Earth might be unique in our galaxy. But now it  seems that there are literally billions of planets with masses similar  to Earth orbiting stars in the Milky Way,&#8221; concludes Daniel Kuba, of the  European Southern Observatory and co-lead author of the paper .</p>
<div>###</div>
<p>Founded in 1952, Lawrence Livermore National Laboratory (<a href="http://www.llnl.gov/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.llnl.gov/?referer=');">www.llnl.gov</a>)  provides solutions to our nation&#8217;s most important national security  challenges through innovative science, engineering and technology.  Lawrence Livermore National Laboratory is managed by Lawrence Livermore  National Security, LLC for the U.S. Department of Energy&#8217;s National  Nuclear Security Administration.</p>
<p>Contact: Anne Stark<br />
<a href="mailto:stark8@llnl.gov" target="_blank">stark8@llnl.gov</a><br />
925-422-9799<br />
<a href="http://www.llnl.gov/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.llnl.gov/?referer=');">DOE/Lawrence Livermore National Laboratory</a></p>
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		<title>Astronomers reach new frontiers of dark matter</title>
		<link>http://chattahbox.com/science/2012/01/09/astronomers-reach-new-frontiers-of-dark-matter/</link>
		<comments>http://chattahbox.com/science/2012/01/09/astronomers-reach-new-frontiers-of-dark-matter/#comments</comments>
		<pubDate>Mon, 09 Jan 2012 20:36:35 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47765</guid>
		<description><![CDATA[For the first time, astronomers have mapped dark matter on the largest scale ever observed. The results, presented by Dr Catherine Heymans of the University of Edinburgh, Scotland, and Associate Professor Ludovic Van Waerbeke of the University of British Columbia, Vancouver, Canada, are being presented today to the American Astronomical Society meeting in Austin, Texas. [...]]]></description>
			<content:encoded><![CDATA[<p>For the first time, astronomers have mapped dark matter on the  largest scale ever observed. The results, presented by Dr Catherine  Heymans of the University of Edinburgh, Scotland, and Associate  Professor Ludovic Van Waerbeke of the University of British Columbia,  Vancouver, Canada, are being presented today to the American  Astronomical Society meeting in Austin, Texas. Their findings reveal a  Universe comprised of an intricate cosmic web of dark matter and  galaxies spanning more than one billion light years.</p>
<p>An  international team of researchers lead by Van Waerbeke and Heymans  achieved their results by analysing images of about 10 million galaxies  in four different regions of the sky. They studied the distortion of the  light emitted from these galaxies, which is bent as it passes massive  clumps of dark matter during its journey to Earth.</p>
<p>Their project,  known as the Canada-France-Hawaii Telescope Lensing Survey (CFHTLenS),  uses data from the Canada-France-Hawaii Telescope Legacy Survey. This  accumulated images over five years using the wide field imaging camera  MegaCam, a 1 degree by 1 degree field-of-view, 340 Megapixel camera on  the CFHT in Hawaii.</p>
<p>Galaxies included in the survey are  typically six billion light years away. The light captured by the images  used in the study was emitted when the Universe was six billion years  old  &#8211;  roughly half the age it is today.</p>
<p>The team&#8217;s result has  been suspected for a long time from studies based on computer  simulations, but was difficult to verify owing to the invisible nature  of dark matter. This is the first direct glimpse at dark matter on large  scales showing the cosmic web in all directions.</p>
<p>Professor  Ludovic Van Waerbeke, from the University of British Columbia, said: &#8220;It  is fascinating to be able to &#8216;see&#8217; the dark matter using space-time  distortion. It gives us privileged access to this mysterious mass in the  Universe which cannot be observed otherwise. Knowing how dark matter is  distributed is the very first step towards understanding its nature and  how it fits within our current knowledge of physics.&#8221;</p>
<p>Dr  Catherine Heymans, a Lecturer in the University of Edinburgh&#8217;s School of  Physics and Astronomy, said: &#8220;By analysing light from the distant  Universe, we can learn about what it has travelled through on its  journey to reach us. We hope that by mapping more dark matter than has  been studied before, we are a step closer to understanding this material  and its relationship with the galaxies in our Universe.&#8221;</p>
<p>Dr  Christian Veillet, CFHT Executive Director, said &#8220;This dark matter study  illustrates the strong legacy value of the CFHT Legacy Survey which is  now enabling exciting results obtained by teams from many nations which  use the images retrieved from the Canadian Astronomy Data Centre where  they are archived and publicly available&#8221;.</p>
<p>Professor Lance  Miller, from Oxford University said: &#8220;This result has been achieved  through advances in our analysis techniques which we are now applying to  data from the Very Large Telescope&#8217;s (VLT) Survey Telescope in Chile.&#8221;</p>
<p>Professor  Koen Kuijken, from Leiden University, said: &#8220;Over the next three years  we will image more than 10 times the area mapped by CFHTLenS, bringing  us ever closer to our goal of understanding the mysterious dark side of  the Universe.&#8221;</p>
<div>###</div>
<p>Image  Caption: The observations show that dark matter in the Universe is  distributed as a network of gigantic dense (white) and empty (dark)  regions, where the largest white regions are about the size of an Earth  moon on the sky. Credit: Van Waerbeke, Heymans and the CFHTLenS  Collaboration</p>
<p>More images are available at:<br />
<a href="http://www.cfhtlens.org/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.cfhtlens.org/?referer=');">www.cfhtlens.org</a><br />
<a href="http://www.cfht.hawaii.edu/en/news/CFHTLens" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.cfht.hawaii.edu/en/news/CFHTLens?referer=');">www.cfht.hawaii.edu/en/news/CFHTLens</a></p>
<p>This  research was supported by the European Research Council, Natural  Sciences and Engineering Research Council of Canada, the Canadian  Institute for Advanced Research and the Canadian Astronomy Data Centre.</p>
<p>Contact: Catriona Kelly<br />
<a href="mailto:catriona.kelly@ed.ac.uk" target="_blank">catriona.kelly@ed.ac.uk</a><br />
44-131-651-4401<br />
<a href="http://www.ed.ac.uk/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.ed.ac.uk/?referer=');">University of Edinburgh</a></p>
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		<title>Earth&#8217;s massive extinction: The story gets worse</title>
		<link>http://chattahbox.com/science/2012/01/06/earths-massive-extinction-the-story-gets-worse/</link>
		<comments>http://chattahbox.com/science/2012/01/06/earths-massive-extinction-the-story-gets-worse/#comments</comments>
		<pubDate>Fri, 06 Jan 2012 18:21:41 +0000</pubDate>
		<dc:creator>Bear</dc:creator>
				<category><![CDATA[Science]]></category>

		<guid isPermaLink="false">http://chattahbox.com/?p=47758</guid>
		<description><![CDATA[Scientists have uncovered a lot about the Earth&#8217;s greatest extinction event that took place 250 million years ago when rapid climate change wiped out nearly all marine species and a majority of those on land. Now, they have discovered a new culprit likely involved in the annihilation: an influx of mercury into the eco-system. &#8220;No [...]]]></description>
			<content:encoded><![CDATA[<p>Scientists have uncovered a lot about the Earth&#8217;s greatest extinction  event that took place 250 million years ago when rapid climate change  wiped out nearly all marine species and a majority of those on land.  Now, they have discovered a new culprit likely involved in the  annihilation: an influx of mercury into the eco-system.</p>
<p>&#8220;No one  had ever looked to see if mercury was a potential culprit. This was a  time of the greatest volcanic activity in Earth&#8217;s history and we know  today that the largest source of mercury comes from volcanic eruptions,&#8221;  says Dr. Steve Grasby, co-author of a paper published this month in the  journal <em>Geology</em>. &#8220;We estimate that the mercury released then  could have been up to 30 times greater than today&#8217;s volcanic activity,  making the event truly catastrophic.&#8221; Grasby is a research scientist at  Natural Resources Canada and an adjunct professor at the University of  Calgary.</p>
<p>Dr. Benoit Beauchamp, professor of geology at the  University of Calgary, says this study is significant because it&#8217;s the  first time mercury has been linked to the cause of the massive  extinction that took place during the end of the Permian.</p>
<p>&#8220;Geologists,  including myself should be taking notes and taking another look at the  other five big extinction events,&#8221; says Beauchamp, also a co-author.</p>
<p>During  the late Permian, the natural buffering system in the ocean became  overloaded with mercury contributing to the loss of 95 per cent of life  in the sea.</p>
<p>&#8220;Typically, algae acts like a scavenger and buries  the mercury in the sediment, mitigating the effect in the oceans,&#8221; says  lead-author Dr. Hamed Sanei, research scientist at Natural Resources  Canada and adjunct professor at the University of Calgary. &#8220;But in this  case, the load was just so huge that it could not stop the damage.&#8221;</p>
<p>About  250 million years ago, a time long before dinosaurs ruled and when all  land formed one big continent, the majority of life in the ocean and on  land was wiped out. The generally accepted idea is that volcanic  eruptions burned though coal beds, releasing CO2 and other deadly  toxins. Direct proof of this theory was outlined in a paper that was  published by these same authors last January in <em>Nature Geoscience</em>.</p>
<p>The  mercury deposition rates could have been significantly higher in the  late Permian when compared with today&#8217;s human-caused emissions. In some  cases, levels of mercury in the late Permian ocean was similar to what  is found near highly contaminated ponds near smelters, where the aquatic  system is severely damaged, say researchers.</p>
<p>&#8220;We are adding to  the levels through industrial emissions. This is a warning for us here  on Earth today,&#8221; adds Beauchamp. Canada has taken a lead role in  reducing emissions internationally. In North America, at least, there  has been a steady decline through regulations controlling mercury.</p>
<p>No  matter what happens, this study shows life&#8217;s tenacity. &#8220;The story is  one of recovery as well. After the system was overloaded and most of  life was destroyed, the oceans were still able to self clean and we were  able to move on to the next phase of life,&#8221; says Sanei.</p>
<p>Contact: Leanne Yohemas<br />
<a href="mailto:lmyohema@ucalgary.ca" target="_blank">lmyohema@ucalgary.ca</a><br />
403-540-6552<br />
<a href="http://www.ucalgary.ca/" target="_blank" onclick="pageTracker._trackPageview('/outgoing/www.ucalgary.ca/?referer=');">University of Calgary</a></p>
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