Gene Variation Linked To Painful Side Effects Of Statins

July 24, 2008

A new study has linked painful side effects experience by people who take cholesterol lowering drugs known as statins, to a gene variation...Boston (ChattahBox) – A new study has linked painful side effects experience by people who take cholesterol lowering drugs known as statins, to a gene variation.

The study was led by Rory Collins, a British Heart Foundation professor at Oxford University, and looked at side effectst caused by statins including weakness, as well as muscle pain.

British scientists were able to link a variation of the gene known as SLCO1B1 as responsible for 60% of the cases of the side effects, known as myopathy.

Myopathy is a term for the severe muscle pain and weakness caused by statins when taken in high doses.

Scientists, reporting in the New England Journal of Medicine, and the hope is that scientists can develop a blood test to determine if people are at risk of the side effect before taking statins.


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