New E. Coli Vaccine: Could Save Millions of Children’s Lives

April 15, 2009

(ChattahBox)—Michigan State University researcher, A. Mahdi Saeed has devoted four years of his professional life searching for a workable vaccine to combat the deadly E. coli bacteria, and it looks like he finally succeeded. Saeed developed a vaccine for the Enterotoxigenic E. coli strain, which causes 60 to 70 percent of all E. coli diarrheal disease and is responsible for killing up to 3 million children every year.

E. coli bacteria is a widespread global problem affecting U.S. troops serving overseas, and is responsible for traveler’s diarrhea, which has ruined many an intrepid traveler’s vacation plans.

The tiny molecular size of one of the toxins of the E. coli remained resistant in the past to any vaccines, because it was too small to trigger an immune response in the body.

Saeed solved this problem by developing a biological carrier that attached to the toxin that produced a strong immune response. After immunizing a group of 10 rabbits, the vaccine produced the highest neutralizing antibody ever reported for this type of the toxin.

This new vaccine will also work on animals and has exciting veterinary applications to prevent the deaths of many newborn farm animals, who are highly susceptible to E. coli bacteria.

Saeed plans to conduct human clinical trials later this year and he has applied for a patent for his new vaccine technique, with plans to commercially produce the vaccine as soon as possible.

This new vaccine has tremendous worldwide applications to save millions of children’s lives.

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