Crack-Cocaine Vaccine Kills the High, But Not for Everyone

October 6, 2009

(ChattahBox)—A new vaccine to treat cocaine addiction was effective in killing the high for some users, helping them kick their addictions, but has a ways to go before it offers a true cure. The cocaine vaccine was successful in producing antibodies to the highly addictive drug in about a third of study participants, but only for a short duration.

The vaccine was tested on addicts in a 6-month trial study and although the results were mixed, the vaccine represents the first drug to show promise, as a treatment for cocaine addiction.

The study was conducted, by Dr. Bridget A. Martell, of Yale University School of Medicine, New Haven, and Veterans Affairs Connecticut Healthcare System, West Haven.

The vaccine was tested on 94 adults, mostly white men, who were users of crack cocaine and also in methadone maintenance programs for opioid addiction. The addicts were given the vaccine in a random trial, with some participants receiving a placebo.

Of the participants given the vaccine, about 38 percent showed the desired levels of antibodies to cocaine. However, the antibodies decreased after two months, requiring regular booster shots to maintain the needed antibodies to fight addiction.

Additionally, the study group were also addicted to opiates and were undergoing a methadone-maintenance program, making it difficult to translate the study results to patients addicted solely to crack-cocaine.

However, researchers see potential for the vaccine as part of a comprehensive treatment program, which also includes cognitive behavioral therapy. And the vaccine could spur the development of vaccines to cure addictions to other drugs.

Dr. Nora Volkow, director of the U.S. National Institute on Drug Abuse said, “These findings are transformative in their ability to show for the first time positive results in cocaine addiction. This may be a promising approach as a strategy to address other types of drug addiction. This opens up a series of new opportunities.”

The study is available in the October issue of the Archives of General Psychiatry.

Source


Comments

2 Responses to “Crack-Cocaine Vaccine Kills the High, But Not for Everyone”

  1. Crack-Cocaine Vaccine Kills the High, But Not for Everyone on October 6th, 2009 11:47 pm

    […] More info…(ChattahBox)A new vaccine to treat cocaine addiction was effective in killing the high for some users, helping them kick their addictions, but has a ways to go before it offers a true cure. The cocaine vaccine was successful in producing antibodies to the highly addictive drug in about a third of study participants, but only for a short duration. The vaccine was tested on addicts in a 6-month trial study and although the results were mixed, the vaccine represents the first drug to show promi […]

  2. michael DiCenzo,Jr on October 11th, 2009 3:02 am

    I have had a crack-cocaine addiction for 15 years, it has been horrific for me and my family,I really want to try the vaccine. I have been all over the world to treament centers.I would only get clean for 9months at a time,so please let me know if ,I’m able to receive it or not.

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