Researchers Link Gene To Common Heart Disease

January 3, 2009

US (ChattahBox) – Every year millions of people under the age of 40 develop coronary artery disease, a condition which often leads to heart attacks. Even more frightening? Often, they never know they have it.

But a new study by Duke University Medical School thinks it may have found a gene that predicts whether or not someone is at risk of developing coronary artery disease (CAD), and may perhaps lead to a way of treating it, before heart conditions become a reality.

“These young patients are a vulnerable population on whom coronary artery disease has a significant long-term impact, but they are particularly hard to identify and therefore to initiate preventive therapies for,” Dr Svati Shah, co-author of the study, explained. “These and other genetic findings may help us in the future to identify these patients prior to development of coronary artery disease or their first heart attack.”

The principle if based on a mutant gene that seems to be passed from generation to generation, effecting most in the line as the variant progresses.

“If you had 1 or 2 copies of this mutant version of the gene, there could be a change in NPY level,” said Dr Shah. “The concept is that small changes over time can promote atherosclerosis (hardening of the arteries) at a very young age.”
So far, studies performed on mice seem to corroborate this theory.


One Response to “Researchers Link Gene To Common Heart Disease”

  1. James Garrison on January 12th, 2009 5:16 pm

    I wonder if the gene also has any links to excess weight genes, I know more were uncovered recently.. I weigh 694lbs and im blogging the whole experience, all the way down to my goal of 300. Im personally pretty afraid of these things is why im trying to get the weight off now.


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